Reactome | SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol

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SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10987906] monocarboxylic acid transmembrane transporter activity of SLC16A1:BSG [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10987908
displayName	SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol
eventOf	[Pathway:R-CEL-9749641] Aspirin ADME - Caenorhabditis elegans [Pathway:R-CEL-433692] Proton-coupled monocarboxylate transport - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-561253] SLC22A12 exchanges extracellular urate for cytosolic LACT - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-9645220] SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-351626] H+ [extracellular region] [DefinedSet:R-ALL-433683] MCT substrates [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [DefinedSet:R-ALL-433686] MCT substrates [cytosol]
precedingEvent	[Reaction:R-CEL-561253] SLC22A12 exchanges extracellular urate for cytosolic LACT - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9645220
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-9749641] Aspirin ADME [Pathway:R-CEL-433692] Proton-coupled monocarboxylate transport
(precedingEvent)	[Reaction:R-CEL-561253] SLC22A12 exchanges extracellular urate for cytosolic LACT
(inferredTo)	[Reaction:R-HSA-9645220] SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol

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