Reactome | CDK6 binds RUNX1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10983749
displayName	CDK6 binds RUNX1
eventOf	[Pathway:R-CEL-8934593] Regulation of RUNX1 Expression and Activity - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8938853] CDK6 binds RUNX1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-141283] CDK6 [nucleoplasm] [DefinedSet:R-CEL-8938850] RUNX1,RUNX1:CBFB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CDK6 binds RUNX1
output	[Complex:R-CEL-8938854] RUNX1,RUNX1:CBFB:CDK6 [nucleoplasm]
precedingEvent	[Reaction:R-CEL-8865320] CBFB binds RUNX1 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8938853
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-8934593] Regulation of RUNX1 Expression and Activity
(inferredTo)	[Reaction:R-HSA-8938853] CDK6 binds RUNX1