Reactome | WWOX binds TFAP2C

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10981463
displayName	WWOX binds TFAP2C
eventOf	[Pathway:R-CEL-8866904] Negative regulation of activity of TFAP2 (AP-2) family transcription factors - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8864569] WWOX binds TFAP2C - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-8864579] aptf-1 [cytosol] [EntityWithAccessionedSequence:R-CEL-1253335] WWOX [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	WWOX binds TFAP2C
output	[Complex:R-CEL-8864568] TFAP2C:WWOX [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8864569
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-8866904] Negative regulation of activity of TFAP2 (AP-2) family transcription factors
(inferredTo)	[Reaction:R-HSA-8864569] WWOX binds TFAP2C