Reactome | Regulation of IFNG signaling

Schema > Pathway > Entries

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10994881
displayName	Regulation of IFNG signaling
eventOf	[Pathway:R-CEL-877300] Interferon gamma signaling - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:383880] regulation of type II interferon-mediated signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-877281] PIAS1 binds p-STAT1 dimer - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-877312] Regulation of IFNG signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Regulation of IFNG signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-877312
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-877300] Interferon gamma signaling
(inferredTo)	[Pathway:R-HSA-877312] Regulation of IFNG signaling

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