Reactome | Binding of ADAR2 homodimer to dsRNA duplex

Schema > Reaction > Entries

Binding of ADAR2 homodimer to dsRNA duplex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10920719
displayName	Binding of ADAR2 homodimer to dsRNA duplex
eventOf	[Pathway:R-CEL-77042] Formation of editosomes by ADAR proteins - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-77615] Deamination at C6 position of adenosine in Editosome (ADAR2) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-77613] Binding of ADAR2 homodimer to dsRNA duplex - Homo sapiens
input	[Complex:R-CEL-111235] ADAR2 homodimer [nucleoplasm] [OtherEntity:R-ALL-75086] dsRNA duplex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Binding of ADAR2 homodimer to dsRNA duplex
output	[Complex:R-CEL-77610] Editosome (ADAR2) complex [nucleoplasm]
precedingEvent	[Reaction:R-CEL-111238] Formation of ADAR2 homodimer - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-77613
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-CEL-77615] Deamination at C6 position of adenosine in Editosome (ADAR2)
(hasEvent)	[Pathway:R-CEL-77042] Formation of editosomes by ADAR proteins
(inferredTo)	[Reaction:R-HSA-77613] Binding of ADAR2 homodimer to dsRNA duplex

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