Reactome | DHRS7B reduces GO3P to HXDG3P

Schema > Reaction > Entries

DHRS7B reduces GO3P to HXDG3P Show undefined attributes

catalystActivity	[CatalystActivity:10919534] acylglycerone-phosphate reductase (NADP+) activity of DHRS7B [peroxisomal membrane]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10919536
displayName	DHRS7B reduces GO3P to HXDG3P
eventOf	[Pathway:R-CEL-75896] Plasmalogen biosynthesis - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-75883] DHRS7B reduces GO3P to HXDG3P - Homo sapiens
input	[SimpleEntity:R-ALL-75973] GO3P [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DHRS7B reduces GO3P to HXDG3P O-hexadecylglycerone phosphate + NADPH + H+ => 1-hexadecyl glycerol-3-phosphate + NADP+ Conversion of acylated DHAP to lysophosphatidic acid
output	[SimpleEntity:R-ALL-390422] HXDG3P [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-75883
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-75896] Plasmalogen biosynthesis
(precedingEvent)	[Reaction:R-CEL-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT)
(inferredTo)	[Reaction:R-HSA-75883] DHRS7B reduces GO3P to HXDG3P

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