Reactome | SLC29A3 transports nucleosides from cytosol to lysosomal lumen

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SLC29A3 transports nucleosides from cytosol to lysosomal lumen Show undefined attributes

catalystActivity	[CatalystActivity:10942236] nucleoside transmembrane transporter activity of SLC29A3 [lysosomal membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17938] lysosomal membrane [Compartment:161320] lysosomal lumen
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10942248
displayName	SLC29A3 transports nucleosides from cytosol to lysosomal lumen
eventOf	[Pathway:R-CEL-83936] Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-727767] SLC29A3 transports nucleosides from cytosol to lysosomal lumen - Homo sapiens
input	[DefinedSet:R-ALL-727746] nucleosides [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC29A3 transports nucleosides from cytosol to lysosomal lumen Equilibrative transport (import) of nucleosides and adenine by solute carrier family 29 (nucleoside transporters), member 3
output	[DefinedSet:R-ALL-727782] nucleosides [lysosomal lumen]
precedingEvent	[Reaction:R-CEL-109530] Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 - Caenorhabditis elegans [Reaction:R-CEL-109538] Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 - Caenorhabditis elegans [Reaction:R-CEL-109539] Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 - Caenorhabditis elegans [Reaction:R-CEL-109536] Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 - Caenorhabditis elegans [Reaction:R-CEL-109527] Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-727767
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-83936] Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
(inferredTo)	[Reaction:R-HSA-727767] SLC29A3 transports nucleosides from cytosol to lysosomal lumen