Reactome | NAAA hydrolyses NAEs to FAs and ethanolamine

Schema > Reaction > Entries

NAAA hydrolyses NAEs to FAs and ethanolamine Show undefined attributes

catalystActivity	[CatalystActivity:10977695] hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds of NAAA dimer [lysosomal lumen]
category	transition
compartment	[Compartment:161320] lysosomal lumen
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10977697
displayName	NAAA hydrolyses NAEs to FAs and ethanolamine
eventOf	[Pathway:R-CEL-112310] Neurotransmitter release cycle - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6803753] NAAA hydrolyses NAEs to FAs and ethanolamine - Homo sapiens
input	[SimpleEntity:R-ALL-1605715] H2O [lysosomal lumen] [DefinedSet:R-ALL-6803725] NAEs [lysosomal lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	NAAA hydrolyses NAEs to FAs and ethanolamine
output	[SimpleEntity:R-ALL-6803745] ETA [lysosomal lumen] [DefinedSet:R-ALL-6803778] FAs [lysosomal lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6803753
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-112310] Neurotransmitter release cycle
(inferredTo)	[Reaction:R-HSA-6803753] NAAA hydrolyses NAEs to FAs and ethanolamine

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