Reactome | GPX5,6 reduce H2O2 to H2O

Schema > Reaction > Entries

GPX5,6 reduce H2O2 to H2O Show undefined attributes

catalystActivity	[CatalystActivity:10976839] glutathione peroxidase activity of GPX5, (GPX6) [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10976841
displayName	GPX5,6 reduce H2O2 to H2O
eventOf	[Pathway:R-CEL-3299685] Detoxification of Reactive Oxygen Species - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6799695] GPX5,6 reduce H2O2 to H2O - Homo sapiens
input	2 × [SimpleEntity:R-ALL-1247892] GSH [extracellular region] 2 × [SimpleEntity:R-ALL-351629] H2O2 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	GPX5,6 reduce H2O2 to H2O
output	[SimpleEntity:R-ALL-3341331] GSSG [extracellular region] 2 × [SimpleEntity:R-ALL-109276] H2O [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6799695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-3299685] Detoxification of Reactive Oxygen Species
(inferredTo)	[Reaction:R-HSA-6799695] GPX5,6 reduce H2O2 to H2O

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