Reactome | FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc

Schema > Reaction > Entries

FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc Show undefined attributes

catalystActivity	[CatalystActivity:10972545] fucose-1-phosphate guanylyltransferase activity of FPGT [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10972547
displayName	FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc
eventOf	[Pathway:R-CEL-6787639] GDP-fucose biosynthesis - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-6787533] FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc - Homo sapiens
input	[SimpleEntity:R-ALL-6787542] Fuc1P [cytosol] [SimpleEntity:R-ALL-29438] GTP [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc beta-L-fucose 1-phosphate + GTP + H(+) => GDP-beta-L-fucose + diphosphate
output	[SimpleEntity:R-ALL-742368] GDP-Fuc [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-CEL-6787540] FCSK phosphorylates beta-Fuc to Fuc1P - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6787533
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-6787639] GDP-fucose biosynthesis
(precedingEvent)	[Reaction:R-CEL-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen
(inferredTo)	[Reaction:R-HSA-6787533] FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc

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