Reactome | ATXN3 binds polyUb-PARK2

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ATXN3 binds polyUb-PARK2 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10969873
displayName	ATXN3 binds polyUb-PARK2
eventOf	[Pathway:R-CEL-5689877] Josephin domain DUBs - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-5688837] ATXN3 deubiquitinates polyUb-PARK2 - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-5689085] ATXN3 binds polyUb-PARK2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-5625607] atx-3 [cytosol] [EntityWithAccessionedSequence:R-CEL-5689094] pdr-1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATXN3 binds polyUb-PARK2
output	[Complex:R-CEL-5689561] ATXN3:polyUb-PARK2 [cytosol]
precedingEvent	[Reaction:R-CEL-5689111] PARK2 autoubiquitinates - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5689085
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-5689877] Josephin domain DUBs
(precedingEvent)	[Reaction:R-CEL-5688837] ATXN3 deubiquitinates polyUb-PARK2
(inferredTo)	[Reaction:R-HSA-5689085] ATXN3 binds polyUb-PARK2

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