Reactome | ATP6AP1 binds V-ATPase

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ATP6AP1 binds V-ATPase Show undefined attributes

category	binding
compartment	[Compartment:171062] early endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10964683
displayName	ATP6AP1 binds V-ATPase
eventOf	[Pathway:R-CEL-917977] Transferrin endocytosis and recycling - Caenorhabditis elegans [Pathway:R-CEL-983712] Ion channel transport - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-74723] Endosome acidification - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-5252133] ATP6AP1 binds V-ATPase - Homo sapiens
input	[Complex:R-CEL-912600] V-ATPase [endosome membrane] [EntityWithAccessionedSequence:R-CEL-5215981] vha-19 [endosome membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ATP6AP1 binds V-ATPase
output	[Complex:R-CEL-5252081] V-ATPase:ATP6AP1 [endosome membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5252133
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-983712] Ion channel transport [Pathway:R-CEL-917977] Transferrin endocytosis and recycling [Pathway:R-CEL-77387] Insulin receptor recycling
(precedingEvent)	[Reaction:R-CEL-74723] Endosome acidification
(inferredTo)	[Reaction:R-HSA-5252133] ATP6AP1 binds V-ATPase