Reactome | Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3

Schema > Reaction > Entries

Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 Show undefined attributes

category	transition
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10939373
displayName	Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3
eventOf	[Pathway:R-CEL-450302] activated TAK1 mediates p38 MAPK activation - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-450257] Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 - Homo sapiens
input	[Complex:R-CEL-450254] p-p38 MAPK:p-MAPKAPK2/3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3
output	[Complex:R-CEL-450241] p-p38 MAPK: p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol]
precedingEvent	[Reaction:R-CEL-450222] Active p38 MAPK phosphorylates MAPKAPK2 or 3 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-450257
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-450302] activated TAK1 mediates p38 MAPK activation
(inferredTo)	[Reaction:R-HSA-450257] Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3

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