Reactome | GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region

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GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10939340] D-glucose transmembrane transporter activity of GLUT2 / SLC2A2 tetramer [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10939342
displayName	GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region
eventOf	[Pathway:R-CEL-189200] Cellular hexose transport - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-450095] GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-70113] Glc [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region alpha-D-glucose (cytosol) <=> alpha-D-glucose (extracellular) Glucose is secreted across the plasma membrane
output	[SimpleEntity:R-ALL-70115] Glc [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-450095
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-189200] Cellular hexose transport
(inferredTo)	[Reaction:R-HSA-450095] GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region

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