Reactome | Activation of AMPA receptors

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Activation of AMPA receptors Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10994659
displayName	Activation of AMPA receptors
eventOf	[Pathway:R-CEL-399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-420977] Ca permeable AMPA receptor ligand binding - Caenorhabditis elegans [Reaction:R-CEL-399712] Activation of Ca permeable AMPA receptors - Caenorhabditis elegans [Reaction:R-CEL-420980] Activation of Ca permeable AMPA receptors - Caenorhabditis elegans [Reaction:R-CEL-420975] Ca impermeable AMPA receptor ligand binding - Caenorhabditis elegans [Reaction:R-CEL-399711] Activation of Ca impermeable AMPA receptors - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-399710] Activation of AMPA receptors - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of AMPA receptors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-399710
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-399721] Glutamate binding, activation of AMPA receptors and synaptic plasticity
(inferredTo)	[Pathway:R-HSA-399710] Activation of AMPA receptors