Reactome | ADRA2A,B,C bind ADR,NAd

Schema > Reaction > Entries

ADRA2A,B,C bind ADR,NAd Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10934930
displayName	ADRA2A,B,C bind ADR,NAd
eventOf	[Pathway:R-CEL-392023] Adrenaline signalling through Alpha-2 adrenergic receptor - Caenorhabditis elegans [Pathway:R-CEL-390696] Adrenoceptors - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-390663] ADRA2A,B,C bind ADR,NAd - Homo sapiens
input	[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region] [DefinedSet:R-CEL-390664] ADRA2A,B,C [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	ADRA2A,B,C bind ADR,NAd Alpha-2 adrenoceptors bind catecholamines
output	[Complex:R-CEL-390700] ADRA2A,B,C:ADR,NAd [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-390663
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-392023] Adrenaline signalling through Alpha-2 adrenergic receptor [Pathway:R-CEL-390696] Adrenoceptors
(precedingEvent)	[Reaction:R-CEL-749446] Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz
(inferredTo)	[Reaction:R-HSA-390663] ADRA2A,B,C bind ADR,NAd