Reactome | SEMA4D interacts with CD45

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10932124
displayName	SEMA4D interacts with CD45
eventOf	[Pathway:R-CEL-416700] Other semaphorin interactions - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-373746] SEMA4D interacts with CD45 - Homo sapiens
input	[DefinedSet:R-CEL-197744-4] Homologues of SEMA4D [plasma membrane] [EntityWithAccessionedSequence:R-CEL-197931] PTPRC [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	SEMA4D interacts with CD45
output	[Complex:R-CEL-373689] SEMA4D:PTPRC [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-373746
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-416700] Other semaphorin interactions
(inferredTo)	[Reaction:R-HSA-373746] SEMA4D interacts with CD45

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