Reactome | Translocation of PTK2 to Focal complexes

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Translocation of PTK2 to Focal complexes Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10931760
displayName	Translocation of PTK2 to Focal complexes
eventOf	[Pathway:R-CEL-354192] Integrin signaling - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-354073] Autophosphorylation of PTK2 at Y397 - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-354066] Translocation of PTK2 to Focal complexes - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-201621] PTK2 [cytosol] [Complex:R-CEL-377622] Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of PTK2 to Focal complexes
output	[Complex:R-CEL-354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]
precedingEvent	[Reaction:R-CEL-377640] Autophosphorylation of SRC - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-354066
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-354192] Integrin signaling
(precedingEvent)	[Reaction:R-CEL-354073] Autophosphorylation of PTK2 at Y397
(inferredTo)	[Reaction:R-HSA-354066] Translocation of PTK2 to Focal complexes

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