Reactome | cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)

Schema > Reaction > Entries

cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) Show undefined attributes

catalystActivity	[CatalystActivity:10931065] phosphatidylcholine-sterol O-acyltransferase activity of LCAT [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10931067
displayName	cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)
eventOf	[Pathway:R-CEL-8964058] HDL remodeling - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-264695] cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) - Homo sapiens
input	[SimpleEntity:R-ALL-171149] CHOL [extracellular region] [SimpleEntity:R-ALL-382539] PC [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)
output	[SimpleEntity:R-ALL-194236] 1-acyl LPC [extracellular region] [SimpleEntity:R-ALL-171076] CHEST [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-264695
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-8964058] HDL remodeling
(inferredTo)	[Reaction:R-HSA-264695] cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin)

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