Reactome | cGMP:CNG transports Na+ and Ca2+ into the rod outer segment

Schema > Reaction > Entries

cGMP:CNG transports Na+ and Ca2+ into the rod outer segment Show undefined attributes

catalystActivity	[CatalystActivity:10958302] intracellularly cyclic nucleotide-activated monoatomic cation channel activity of cGMP:CNG channel [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10958304
displayName	cGMP:CNG transports Na+ and Ca2+ into the rod outer segment
eventOf	[Pathway:R-CEL-2485179] Activation of the phototransduction cascade - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2514867] cGMP:CNG transports Na+ and Ca2+ into the rod outer segment - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	cGMP:CNG transports Na+ and Ca2+ into the rod outer segment
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-2514867
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-2485179] Activation of the phototransduction cascade
(inferredTo)	[Reaction:R-HSA-2514867] cGMP:CNG transports Na+ and Ca2+ into the rod outer segment

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