Reactome | CYP2S1 4-hydroxylates atRA

Schema > Reaction > Entries

CYP2S1 4-hydroxylates atRA Show undefined attributes

catalystActivity	[CatalystActivity:10930859] retinoic acid 4-hydroxylase activity of CYP2S1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17960] smooth endoplasmic reticulum
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10930861
displayName	CYP2S1 4-hydroxylates atRA
eventOf	[Pathway:R-CEL-211958] Miscellaneous substrates - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-211874] CYP2S1 4-hydroxylates atRA - Homo sapiens
input	[SimpleEntity:R-ALL-215573] atRA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113534] O2 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP2S1 4-hydroxylates atRA
output	[SimpleEntity:R-ALL-215584] 4OH-atRA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-211874
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-211958] Miscellaneous substrates
(inferredTo)	[Reaction:R-HSA-211874] CYP2S1 4-hydroxylates atRA