Reactome | L-Glutamate loading of synaptic vesicle

Schema > Reaction > Entries

L-Glutamate loading of synaptic vesicle Show undefined attributes

catalystActivity	[CatalystActivity:10930775] L-glutamate transmembrane transporter activity of Empty Glutamate Synaptic Vesicle [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10930777
displayName	L-Glutamate loading of synaptic vesicle
eventOf	[Pathway:R-CEL-210500] Glutamate Neurotransmitter Release Cycle - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-372505] Acetylcholine synaptic vesicle docking and priming - Caenorhabditis elegans [Reaction:R-CEL-210426] Glutamate synaptic vesicle docking and priming - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-210444] L-Glutamate loading of synaptic vesicle - Homo sapiens
input	[Complex:R-CEL-264795] Empty Glutamate Synaptic Vesicle [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	L-Glutamate loading of synaptic vesicle
output	[Complex:R-CEL-210380] Glutamate loaded synaptic vesicle [cytosol]
precedingEvent	[Reaction:R-CEL-210404] SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ - Caenorhabditis elegans [Reaction:R-CEL-70723] leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] - Caenorhabditis elegans [Reaction:R-CEL-70609] glutamine + H2O => glutamate + NH4+ (GLS) - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-210444
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-210500] Glutamate Neurotransmitter Release Cycle
(precedingEvent)	[Reaction:R-CEL-372505] Acetylcholine synaptic vesicle docking and priming [Reaction:R-CEL-210426] Glutamate synaptic vesicle docking and priming
(inferredTo)	[Reaction:R-HSA-210444] L-Glutamate loading of synaptic vesicle