Reactome | p75 NTR receptor-mediated signalling

Schema > Pathway > Entries

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10994293
displayName	p75 NTR receptor-mediated signalling
eventOf	[Pathway:R-CEL-73887] Death Receptor Signaling - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:182] neurotrophin TRK receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-CEL-204998] Cell death signalling via NRAGE, NRIF and NADE - Caenorhabditis elegans [Pathway:R-CEL-193697] p75NTR regulates axonogenesis - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-193704] p75 NTR receptor-mediated signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	p75 NTR receptor-mediated signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-193704
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEncapsulatedEvent)	[Pathway:R-CEL-187037] Signaling by NTRK1 (TRKA)
(hasEvent)	[Pathway:R-CEL-73887] Death Receptor Signaling
(inferredTo)	[Pathway:R-HSA-193704] p75 NTR receptor-mediated signalling

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