Reactome | GBA3 hydrolyzes GlcCer (cytosol)

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10952055] glucosylceramidase activity of GBA3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10952057
displayName	GBA3 hydrolyzes GlcCer (cytosol)
eventOf	[Pathway:R-CEL-9840310] Glycosphingolipid catabolism - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1861789] GBA3 hydrolyzes GlcCer (cytosol) - Homo sapiens
input	[SimpleEntity:R-ALL-1861764] GlcCer [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GBA3 hydrolyzes GlcCer (cytosol)
output	[SimpleEntity:R-ALL-194377] CERA [cytosol] [SimpleEntity:R-ALL-70113] Glc [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1861789
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-9840310] Glycosphingolipid catabolism
(inferredTo)	[Reaction:R-HSA-1861789] GBA3 hydrolyzes GlcCer (cytosol)

Cite Us!