Reactome | EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10924969
displayName	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CEL-182937] ehs-1 [plasma membrane] [EntityWithAccessionedSequence:R-CEL-182952] epn-1 [plasma membrane] [Complex:R-CEL-182947] EPS15:HGS:STAM [cytosol] 2 × [DefinedSet:R-CEL-179863-3] Homologues of EGF [extracellular region] 2 × [EntityWithAccessionedSequence:R-CEL-179803] phospho-p-6Y-EGFR [plasma membrane] 2 × [EntityWithAccessionedSequence:R-CEL-182923] phospho-sli-1 [plasma membrane] [Complex:R-CEL-8934537] Ub-CIN85:endophilin [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] - Homo sapiens
maxDepth	5
name	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15
producedByEvent	[Reaction:R-CEL-182986] CBL-mediated ubiquitination of CIN85 - Caenorhabditis elegans
schemaClass	Complex
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-182936
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-CEL-182986] CBL-mediated ubiquitination of CIN85
(inferredTo)	[Complex:R-HSA-182936] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]

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