Reactome | GLYAT-like proteins transfer glycine to ST-CoA to form SUA

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GLYAT-like proteins transfer glycine to ST-CoA to form SUA Show undefined attributes

catalystActivity	[CatalystActivity:10922732] glycine N-benzoyltransferase activity of GLYAT-like proteins [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10922736
displayName	GLYAT-like proteins transfer glycine to ST-CoA to form SUA
eventOf	[Pathway:R-CEL-177128] Conjugation of salicylate with glycine - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA - Homo sapiens
input	[SimpleEntity:R-ALL-159549] Gly [mitochondrial matrix] [SimpleEntity:R-ALL-159557] ST-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	GLYAT-like proteins transfer glycine to ST-CoA to form SUA salicylate-CoA + glycine => salicyluric acid + Coenzyme A Salicylate-CoA forms an amide bond with glycine
output	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-159572] SUA [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-159574
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-177128] Conjugation of salicylate with glycine
(inferredTo)	[Reaction:R-HSA-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA

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