Reactome | Translesion synthesis by REV1

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Translesion synthesis by REV1 Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10993827
displayName	Translesion synthesis by REV1
eventOf	[Pathway:R-CEL-110313] Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:10327] error-prone translesion synthesis
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-110307] REV1 binds AP-dsDNA - Caenorhabditis elegans [Reaction:R-CEL-110308] REV1 inserts dCMP opposite to AP sites in DNA - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-110312] Translesion synthesis by REV1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Translesion synthesis by REV1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-110312
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-110313] Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
(inferredTo)	[Pathway:R-HSA-110312] Translesion synthesis by REV1

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