Reactome | Formation of the closed pre-initiation complex

Schema > Reaction > Entries

Formation of the closed pre-initiation complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10747140
displayName	Formation of the closed pre-initiation complex
eventOf	[Pathway:R-CEL-73779] RNA Polymerase II Transcription Pre-Initiation And Promoter Opening - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-75949] RNA Polymerase II Promoter Opening: First Transition - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-109639] Formation of the closed pre-initiation complex - Homo sapiens
input	[Complex:R-CEL-75871] pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] [Complex:R-CEL-109634] TFIIH [nucleoplasm]
isInDisease	false
isInferred	true
name	Formation of the closed pre-initiation complex
output	[Complex:R-CEL-109635] pol II closed pre-initiation complex [nucleoplasm]
precedingEvent	[Reaction:R-CEL-75095] Binding of TFIIE to the growing preinitiation complex - Caenorhabditis elegans
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-109639
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-73779] RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
(precedingEvent)	[Reaction:R-CEL-75949] RNA Polymerase II Promoter Opening: First Transition
(inferredTo)	[Reaction:R-HSA-109639] Formation of the closed pre-initiation complex