Reactome | Association of GABA B receptor with G protein beta-gamma subunits

Schema > Reaction > Entries

Association of GABA B receptor with G protein beta-gamma subunits Show undefined attributes

catalystActivity	[CatalystActivity:10946098] G protein-coupled GABA receptor activity of GABBR1:GABBR2:GABA [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10946102
displayName	Association of GABA B receptor with G protein beta-gamma subunits
eventOf	[Pathway:R-CEL-1296041] Activation of G protein gated Potassium channels - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1013012] Binding of Gbeta/gamma to GIRK/Kir3 channels - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-1013013] Association of GABA B receptor with G protein beta-gamma subunits - Homo sapiens
input	[Complex:R-CEL-167434] G-protein beta-gamma complex [plasma membrane] [Complex:R-CEL-420698] GABBR1:GABBR2:GABA [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Association of GABA B receptor with G protein beta-gamma subunits
output	[Complex:R-CEL-1013017] GABA B receptor G-protein beta-gamma complex [plasma membrane]
precedingEvent	[Reaction:R-CEL-420688] GABAB heterodimeric receptor binds GABA - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1013013
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1296041] Activation of G protein gated Potassium channels [Pathway:R-CEL-997272] Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
(precedingEvent)	[Reaction:R-CEL-1013012] Binding of Gbeta/gamma to GIRK/Kir3 channels
(inferredTo)	[Reaction:R-HSA-1013013] Association of GABA B receptor with G protein beta-gamma subunits

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