Reactome | botC:GT1b [synaptic vesicle membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:5250521] protein transmembrane transporter activity of botC:GT1b [synaptic vesicle membrane]
compartment	[Compartment:201753] synaptic vesicle membrane
consumedByEvent	[BlackBoxEvent:R-HSA-5246514] botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol - Homo sapiens
created	[InstanceEdit:5246515] D'Eustachio, Peter, 2014-01-21
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	5246508
deleted	[Deleted:5250997] Deletion of instance: 181477 [Deleted:5251000] Deletion of instance: 194804
disease	[Disease:3632909] botulism
displayName	botC:GT1b [synaptic vesicle membrane]
goCellularComponent	[Compartment:5251407] host cell synaptic vesicle membrane
hasComponent	[Complex:R-CBO-5246524] BoNT/C HC:LC dimer [synaptic vesicle membrane] 2 × [SimpleEntity:R-ALL-5244439] GT1b [synaptic vesicle membrane]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:5246511] Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry
maxDepth	4
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	botC:GT1b BoNT/C:GT1b
producedByEvent	[BlackBoxEvent:R-HSA-5246509] botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane - Homo sapiens
schemaClass	Complex
species	[Species:168825] Clostridium botulinum
stId	R-CBO-5246508
updateTrackers	[UpdateTracker:9901730] Update Tracker - [Complex:5246508] botC:GT1b [synaptic vesicle membrane] - v75:[addName]

(updatedInstance)	[UpdateTracker:9901730] Update Tracker - [Complex:5246508] botC:GT1b [synaptic vesicle membrane] - v75:[addName]
(replacementInstances)	[Deleted:5250997] Deletion of instance: 181477 [Deleted:5251000] Deletion of instance: 194804
(output)	[BlackBoxEvent:R-HSA-5246509] botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane
(input)	[BlackBoxEvent:R-HSA-5246514] botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol
(physicalEntity)	[CatalystActivity:5250521] protein transmembrane transporter activity of botC:GT1b [synaptic vesicle membrane]

Cite Us!