Reactome | botB HC:LC dimer [synaptic vesicle membrane]

Schema > Complex > Entries

compartment	[Compartment:201753] synaptic vesicle membrane
componentOf	[Complex:R-HSA-5244502] botB HC:LC:SYT:GT1b [synaptic vesicle membrane] - Homo sapiens
created	[InstanceEdit:5228949] D'Eustachio, Peter, 2014-01-14
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	5228947
deleted	[Deleted:5251027] Deletion of instance: 181582 [Deleted:5251012] Deletion of instance: 194799
disease	[Disease:3632909] botulism
displayName	botB HC:LC dimer [synaptic vesicle membrane]
goCellularComponent	[Compartment:5251407] host cell synaptic vesicle membrane
hasComponent	[EntityWithAccessionedSequence:R-CBO-181459] botB HC disulfide bonded [synaptic vesicle membrane] [Complex:R-CBO-190043] botB LC:Zn2+ disulfide bonded [synaptic vesicle membrane]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:181709] Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B
maxDepth	3
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	botB HC:LC dimer BoNT/B HC:LC dimer
schemaClass	Complex
species	[Species:168825] Clostridium botulinum
stId	R-CBO-5228947
updateTrackers	[UpdateTracker:9901778] Update Tracker - [Complex:5228947] botB HC:LC dimer [synaptic vesicle membrane] - v75:[addName, updateContainedComponent]

(updatedInstance)	[UpdateTracker:9901778] Update Tracker - [Complex:5228947] botB HC:LC dimer [synaptic vesicle membrane] - v75:[addName, updateContainedComponent]
(replacementInstances)	[Deleted:5251027] Deletion of instance: 181582 [Deleted:5251012] Deletion of instance: 194799
(hasComponent)	[Complex:R-HSA-5244502] botB HC:LC:SYT:GT1b [synaptic vesicle membrane]

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