Reactome | AOC1 dimer oxidizes MeHist

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AOC1 dimer oxidizes MeHist Show undefined attributes

catalystActivity	[CatalystActivity:10409191] histamine oxidase activity of AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10442563
displayName	AOC1 dimer oxidizes MeHist
eventOf	[Pathway:R-BTA-70921] Histidine catabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9970023] AOC1 dimer oxidizes MeHist - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-175991] MeHist [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	AOC1 dimer oxidizes MeHist N(tau)-methylhistamine + O2 + H2O => 1-methylimidazole-4-acetaldehyde + H2O2 + NH4(+)
output	[SimpleEntity:R-ALL-29408] H2O2 [cytosol] [SimpleEntity:R-ALL-9970025] methylimidazole-aldehyde [cytosol] [SimpleEntity:R-ALL-31633] NH4+ [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9970023
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-70921] Histidine catabolism
(inferredTo)	[Reaction:R-HSA-9970023] AOC1 dimer oxidizes MeHist

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