Reactome | ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide

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ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide Show undefined attributes

catalystActivity	[CatalystActivity:10442452] ATP hydrolysis activity of ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10442454
displayName	ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide
eventOf	[Pathway:R-BTA-9954714] PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9955731] ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide - Homo sapiens
input	[Complex:R-BTA-9954910] ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide
output	[Complex:R-BTA-9948294] 60S ribosomal subunit:peptidyl-tRNA with nascent peptide [cytosol] [Complex:R-BTA-9955720] ABCE1:ADP:40S ribosomal subunit [cytosol] [EntityWithAccessionedSequence:R-BTA-9954712] PELO [cytosol] 2 × [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-BTA-9954919] ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-9955731
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9954714] PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
(inferredTo)	[BlackBoxEvent:R-HSA-9955731] ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide

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