Reactome | FNTA:PGGT1B geranylgeranylates GBP5

Schema > Reaction > Entries

FNTA:PGGT1B geranylgeranylates GBP5 Show undefined attributes

catalystActivity	[CatalystActivity:10442243] CAAX-protein geranylgeranyltransferase activity of FNTA:PGGT1B:Zn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10442347
displayName	FNTA:PGGT1B geranylgeranylates GBP5
eventOf	[Pathway:R-BTA-9953170] GBP-mediated host defense - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-9954252] GGC-GBP2, GGC-GBP5 bind furin - Bos taurus
inferredFrom	[Reaction:R-HSA-9954195] FNTA:PGGT1B geranylgeranylates GBP5 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-1031692] GBP5 [cytosol] [SimpleEntity:R-ALL-9947981] GGPP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FNTA:PGGT1B geranylgeranylates GBP5 FNTA:PGGT1B transfers GGPP to GBP5 GBP5 prenylation
output	[EntityWithAccessionedSequence:R-BTA-9954196] GBP5 [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9954195
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9953170] GBP-mediated host defense
(precedingEvent)	[Reaction:R-BTA-9954252] GGC-GBP2, GGC-GBP5 bind furin
(inferredTo)	[Reaction:R-HSA-9954195] FNTA:PGGT1B geranylgeranylates GBP5

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