Reactome | Regulation of PD-L1(CD274) Post-translational modification

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Regulation of PD-L1(CD274) Post-translational modification Show undefined attributes

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10446312
displayName	Regulation of PD-L1(CD274) Post-translational modification
eventOf	[Pathway:R-BTA-9909648] Regulation of PD-L1(CD274) expression - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-BTA-9929356] GSK3B-mediated proteasomal degradation of PD-L1(CD274) - Bos taurus [Pathway:R-BTA-9929491] SPOP-mediated proteasomal degradation of PD-L1(CD274) - Bos taurus [Pathway:R-BTA-9931269] AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) - Bos taurus [Pathway:R-BTA-9931295] PD-L1(CD274) glycosylation and translocation to plasma membrane - Bos taurus
inferredFrom	[Pathway:R-HSA-9909615] Regulation of PD-L1(CD274) Post-translational modification - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Regulation of PD-L1(CD274) Post-translational modification
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-9909615
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9909648] Regulation of PD-L1(CD274) expression
(inferredTo)	[Pathway:R-HSA-9909615] Regulation of PD-L1(CD274) Post-translational modification

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