Reactome | HCFC1, HCFC2 bind the MLL1:MEN1 complex

Schema > Reaction > Entries

HCFC1, HCFC2 bind the MLL1:MEN1 complex Show undefined attributes

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10437573
displayName	HCFC1, HCFC2 bind the MLL1:MEN1 complex
eventOf	[Pathway:R-BTA-9772755] Formation of WDR5-containing histone-modifying complexes - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9821235] HCFC1, HCFC2 bind the MLL1:MEN1 complex - Homo sapiens
input	2 × [DefinedSet:R-BTA-9821240] HCFC1,HCFC2 [nucleoplasm] 2 × [DefinedSet:R-BTA-9821264] MLL1 complex,MLL1 complex:MEN1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	HCFC1, HCFC2 bind the MLL1:MEN1 complex
output	[DefinedSet:R-BTA-9821241] MLL1 complex,MLL1 complex:MEN1:HCFC1,HCFC2 [nucleoplasm]
precedingEvent	[Reaction:R-BTA-9818937] MEN1 binds MLL1 complex - Bos taurus [Reaction:R-BTA-9675026] Formation of the MLL1 complex - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9821235
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9772755] Formation of WDR5-containing histone-modifying complexes
(inferredTo)	[Reaction:R-HSA-9821235] HCFC1, HCFC2 bind the MLL1:MEN1 complex

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