Reactome | (p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xK63PolyUb-K50,p-T357,S358-MLKL [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10437218
displayName	(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xK63PolyUb-K50,p-T357,S358-MLKL [cytosol]
hasComponent	[Polymer:R-BTA-5218908] p-S-RIPK1:p-S199,227-RIPK3 oligomer [cytosol] [EntityWithAccessionedSequence:R-BTA-9793468] phospho-MLKL [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9793487] (p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xK63PolyUb-K50,p-T357,S358-MLKL [cytosol] - Homo sapiens
maxDepth	4
name	(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xK63PolyUb-K50,p-T357,S358-MLKL
producedByEvent	[BlackBoxEvent:R-BTA-9793444] ITCH polyubiquitinates MLKL at K50 - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-9793487
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-BTA-9793444] ITCH polyubiquitinates MLKL at K50
(inferredTo)	[Complex:R-HSA-9793487] (p-S-RIPK1:p-S199,227-RIPK3) oligomer:4xK63PolyUb-K50,p-T357,S358-MLKL [cytosol]

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