Reactome | SQSTM1 oligomerizes

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10436249
displayName	SQSTM1 oligomerizes
eventOf	[Pathway:R-BTA-9755511] KEAP1-NFE2L2 pathway - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9759158] SQSTM1 oligomerizes - Homo sapiens
input	3 × [EntityWithAccessionedSequence:R-BTA-193937] SQSTM1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SQSTM1 oligomerizes
output	[Complex:R-BTA-9759097] SQSTM1 oligomer [cytosol]
regulatedBy	[NegativeRegulation:10436250] Negative regulation by 'K7 ub-SQSTM1 [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9759158
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9755511] KEAP1-NFE2L2 pathway
(inferredTo)	[Reaction:R-HSA-9759158] SQSTM1 oligomerizes

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