Reactome | RIPK3 binds STUB1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10434126
displayName	RIPK3 binds STUB1
eventOf	[Pathway:R-BTA-5675482] Regulation of necroptotic cell death - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-9688831] STUB1 ubiquitinates RIPK3 at K55, K363 - Bos taurus
inferredFrom	[Reaction:R-HSA-9688838] RIPK3 binds STUB1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-450328] RIPK3 [cytosol] [Complex:R-BTA-9688809] STUB1:STUB1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RIPK3 binds STUB1 RIPK3+ STUB1 => RIPK3:CHIP
output	[Complex:R-BTA-9688827] RIPK3:STUB1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9688838
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-5675482] Regulation of necroptotic cell death
(precedingEvent)	[BlackBoxEvent:R-BTA-9688831] STUB1 ubiquitinates RIPK3 at K55, K363
(inferredTo)	[Reaction:R-HSA-9688838] RIPK3 binds STUB1

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