Reactome | TPST1,2 transfer SO4(2-) from PAPS to FVIII

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TPST1,2 transfer SO4(2-) from PAPS to FVIII Show undefined attributes

catalystActivity	[CatalystActivity:10428314] protein-tyrosine sulfotransferase activity of TPST1,2 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10433729
displayName	TPST1,2 transfer SO4(2-) from PAPS to FVIII
eventOf	[Pathway:R-BTA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18677] peptidyl-tyrosine sulfation
inferredFrom	[Reaction:R-HSA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-9668037] F8 [Golgi lumen] 2 × [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	TPST1,2 transfer SO4(2-) from PAPS to FVIII
output	[EntityWithAccessionedSequence:R-BTA-9668036] F8 [Golgi lumen] 2 × [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-BTA-741449] SLC35B2,3 exchange cytosolic PAPS with Golgi PAP - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9668023
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(inferredTo)	[Reaction:R-HSA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII

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