Reactome | ESTG:Me260-ESR1 dimer [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-9634580] ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane] - Bos taurus [Complex:R-BTA-9632399] Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] - Bos taurus
consumedByEvent	[BlackBoxEvent:R-BTA-9634584] Estrogen receptor binds IGF1R and SHC1 in response to estrogen - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10432339
displayName	ESTG:Me260-ESR1 dimer [cytosol]
hasComponent	2 × [SimpleEntity:R-ALL-374146] ESTG [extracellular region] 2 × [EntityWithAccessionedSequence:R-BTA-9632177] Me260-ESR1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9634581] ESTG:Me260-ESR1 dimer [cytosol] - Homo sapiens
maxDepth	2
name	ESTG:Me260-ESR1 dimer
positivelyRegulates	[PositiveRegulation:10432396] Positive regulation by 'ESTG:Me260-ESR1 dimer [cytosol]'
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-9634581
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasComponent)	[Complex:R-BTA-9632399] Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] [Complex:R-BTA-9634580] ESTG:ESR1:p-3Y-IGF1R:SHC1 [plasma membrane]
(input)	[BlackBoxEvent:R-BTA-9634584] Estrogen receptor binds IGF1R and SHC1 in response to estrogen
(regulator)	[PositiveRegulation:10432396] Positive regulation by 'ESTG:Me260-ESR1 dimer [cytosol]'
(inferredTo)	[Complex:R-HSA-9634581] ESTG:Me260-ESR1 dimer [cytosol]