Reactome | NR1H2 binds ABCA1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10432265
displayName	NR1H2 binds ABCA1
eventOf	[Pathway:R-BTA-9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9619756] NR1H2 binds ABCA1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-194209] ABCA1 [plasma membrane] [Complex:R-BTA-9619754] NR1H2:RXRA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	NR1H2 binds ABCA1 LXR beta binds ABCA1
output	[Complex:R-BTA-9619752] NR1H2:RXRA:ABCA1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9619756
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
(inferredTo)	[Reaction:R-HSA-9619756] NR1H2 binds ABCA1