Reactome | High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-BTA-914177] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-914182] 14-3-3 zeta binding allows recruitment of PI3K - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10369521
displayName	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane]
hasComponent	[DefinedSet:R-BTA-914179] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc [plasma membrane] [EntityWithAccessionedSequence:R-BTA-206099] YWHAZ [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-914180] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] - Homo sapiens
maxDepth	7
name	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta
producedByEvent	[Reaction:R-BTA-912757] p-S585-IL3RB binds 14-3-3 proteins - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-914180
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-914182] 14-3-3 zeta binding allows recruitment of PI3K
(output)	[Reaction:R-BTA-912757] p-S585-IL3RB binds 14-3-3 proteins
(hasComponent)	[Complex:R-BTA-914177] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane]
(inferredTo)	[Complex:R-HSA-914180] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane]

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