Reactome | EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2

Schema > Reaction > Entries

EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 Show undefined attributes

catalystActivity	[CatalystActivity:10387100] epoxide hydrolase activity of EPHX2 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10431290
displayName	EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2
eventOf	[Pathway:R-BTA-9018682] Biosynthesis of maresins - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9024993] EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 - Homo sapiens
input	[SimpleEntity:R-ALL-9025001] 13(S),14(S)-epoxy-DHA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate
output	[SimpleEntity:R-ALL-9025011] MaR2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9024993
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9018682] Biosynthesis of maresins
(inferredTo)	[Reaction:R-HSA-9024993] EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2

Cite Us!