Reactome | Interleukin-36 pathway

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445782
displayName	Interleukin-36 pathway
eventOf	[Pathway:R-BTA-446652] Interleukin-1 family signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-8848316] IL36 binds IL1RL2 - Bos taurus [Reaction:R-BTA-8848314] IL36:IL1RL2 binds IL1RAP-1 - Bos taurus [Reaction:R-BTA-8940998] IL36RN, IL1F10 bind IL1RL2 - Bos taurus
inferredFrom	[Pathway:R-HSA-9014826] Interleukin-36 pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Interleukin-36 pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-9014826
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-446652] Interleukin-1 family signaling
(inferredTo)	[Pathway:R-HSA-9014826] Interleukin-36 pathway

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