Reactome | IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10429798
displayName	IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]
hasComponent	[Complex:R-BTA-8848514] IL18R1:IL37,IL37(?-218) [plasma membrane] [EntityWithAccessionedSequence:R-BTA-188067] SIGIRR [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-9008597] IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane] - Homo sapiens
maxDepth	3
name	IL18R1:IL37,IL37(?-218):SIGIRR
negativelyRegulates	[NegativeRegulation:10429808] Negative regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]'
positivelyRegulates	[PositiveRegulation:10429870] Positive regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]'
producedByEvent	[Reaction:R-BTA-9008577] IL37:IL18R1 binds SIGIRR - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-9008597
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[PositiveRegulation:10429870] Positive regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]' [NegativeRegulation:10429808] Negative regulation by 'IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]'
(inferredTo)	[Complex:R-HSA-9008597] IL18R1:IL37,IL37(?-218):SIGIRR [plasma membrane]
(output)	[Reaction:R-BTA-9008577] IL37:IL18R1 binds SIGIRR

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