Reactome | PAK1 binds ARHGEF6

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10428717
displayName	PAK1 binds ARHGEF6
eventOf	[Pathway:R-BTA-8964616] G beta:gamma signalling through CDC42 - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8964605] PAK1:ARHGEF6 complex binds G-protein beta-gamma complex - Bos taurus
inferredFrom	[Reaction:R-HSA-8964619] PAK1 binds ARHGEF6 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-195017] ARHGEF6 [cytosol] [EntityWithAccessionedSequence:R-BTA-162629] PAK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PAK1 binds ARHGEF6
output	[Complex:R-BTA-9014578] Active PAK1:ARHGEF6 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8964619
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-8964616] G beta:gamma signalling through CDC42
(precedingEvent)	[Reaction:R-BTA-8964605] PAK1:ARHGEF6 complex binds G-protein beta-gamma complex
(inferredTo)	[Reaction:R-HSA-8964619] PAK1 binds ARHGEF6