Reactome | RUNX1 binds ESR1

Schema > Reaction > Entries

RUNX1 binds ESR1 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10424633
displayName	RUNX1 binds ESR1
eventOf	[Pathway:R-BTA-8931987] RUNX1 regulates estrogen receptor mediated transcription - Bos taurus [Pathway:R-BTA-9018519] Estrogen-dependent gene expression - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8931981] RUNX1 binds ESR1 - Homo sapiens
input	[Complex:R-BTA-1254381] ESR1 dimer:ESTG [nucleoplasm] [Complex:R-BTA-8865330] RUNX1:CBFB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RUNX1 binds ESR1
output	[Complex:R-BTA-8931986] RUNX1:CBFB:ESR1:estrogen [nucleoplasm]
precedingEvent	[Reaction:R-BTA-8865320] CBFB binds RUNX1 - Bos taurus [Reaction:R-BTA-8939201] ESR dimerizes - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8931981
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9018519] Estrogen-dependent gene expression [Pathway:R-BTA-8931987] RUNX1 regulates estrogen receptor mediated transcription
(inferredTo)	[Reaction:R-HSA-8931981] RUNX1 binds ESR1