Reactome | POMGNT2 transfers GlcNAc to Man-DAG1

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POMGNT2 transfers GlcNAc to Man-DAG1 Show undefined attributes

catalystActivity	[CatalystActivity:10424588] protein O-acetylglucosaminyltransferase activity of POMGNT2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10424590
displayName	POMGNT2 transfers GlcNAc to Man-DAG1
eventOf	[Pathway:R-BTA-8932505] DAG1 core M3 glycosylations - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8931648] B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 - Bos taurus
inferredFrom	[Reaction:R-HSA-8879117] POMGNT2 transfers GlcNAc to Man-DAG1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-5615647] DAG1 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-3499326] UDP-GlcNAc [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	POMGNT2 transfers GlcNAc to Man-DAG1 DAG1 extension by B3GALNT2, POMGNT2, SGK196
output	[EntityWithAccessionedSequence:R-BTA-8931673] DAG1 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-158602] UDP [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-BTA-5615637] POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8879117
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8932505] DAG1 core M3 glycosylations
(precedingEvent)	[Reaction:R-BTA-8931648] B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1
(inferredTo)	[Reaction:R-HSA-8879117] POMGNT2 transfers GlcNAc to Man-DAG1

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