Reactome | CARNMT1 methylates CARN to Anserine

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CARNMT1 methylates CARN to Anserine Show undefined attributes

catalystActivity	[CatalystActivity:10424212] carnosine N-methyltransferase activity of CARNMT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10424214
displayName	CARNMT1 methylates CARN to Anserine
eventOf	[Pathway:R-BTA-70921] Histidine catabolism - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8876789] CARNMT1 methylates CARN to Anserine - Homo sapiens
input	[SimpleEntity:R-ALL-71284] AdoMet [cytosol] [SimpleEntity:R-ALL-6786250] CARN [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CARNMT1 methylates CARN to Anserine carnosine + S-adenosyl-L-methionine => anserine + H(+) + S-adenosyl-L-homocysteine
output	[SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [SimpleEntity:R-ALL-8876775] Anserine [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-BTA-6786245] CARNS1 transforms ATP, L-His, b-Ala to CARN - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8876789
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-70921] Histidine catabolism
(inferredTo)	[Reaction:R-HSA-8876789] CARNMT1 methylates CARN to Anserine

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